Description

2-Oxo-2-Piperazin-1-Yl-Acetamide Hcl is a high-purity pharmaceutical intermediate and building block used in advanced organic synthesis. This compound is valued for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic structures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Used in the research and development (R&D) and scale-up production of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation & Probe Development: Potential use in creating biochemical probes and bioconjugates for diagnostic and research applications due to its reactive functional groups.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialized fine chemicals and advanced materials.

Basic Information

Product Name	2-Oxo-2-Piperazin-1-Yl-Acetamide Hcl
CAS No.	1176419-61-6
Molecular Formula	C6H12N4O2•HCl
Molecular Weight	208.65 g/mol (Free base: 172.19 g/mol)
Synonyms	2-(2-Oxo-2-(piperazin-1-yl)acetamido)acetic acid hydrochloride; 2-Oxo-2-(piperazin-1-yl)acetamide hydrochloride; Glycine, N-(2-oxo-2-(1-piperazinyl)acetyl)-, hydrochloride; 1-Piperazineacetamide, 2-oxo-, hydrochloride; N-(2-Oxo-2-(piperazin-1-yl)acetyl)glycine hydrochloride; (2-Oxo-2-piperazin-1-yl-acetylamino)-acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxo-2-Piperazin-1-Yl-Acetamide Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.