Description

1-Acetyl-4-(2-Hydroxy-Ethyl)-Piperazine Hcl CAS NO 1176419-58-1 is a high-purity piperazine derivative, a crucial building block in advanced organic synthesis. Its value lies in its bifunctional structure, which serves as a versatile intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its piperazine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal complexation processes.
• Polymer Modification: Employed to introduce functional amine and hydroxyl groups into polymer chains, enhancing properties like adhesion, cross-linking, or biocompatibility.
• Bioconjugation and Linker Chemistry: Useful in the development of chemical linkers for antibody-drug conjugates (ADCs) or other bioconjugation applications.
• Chemical Research: A valuable reagent in academic and industrial laboratories for exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	1-Acetyl-4-(2-Hydroxy-Ethyl)-Piperazine Hcl
CAS No.	1176419-58-1
Molecular Formula	C8H17ClN2O2
Molecular Weight	208.69 g/mol
Synonyms	1-Acetyl-4-(2-hydroxyethyl)piperazine hydrochloride; 4-(2-Hydroxyethyl)-1-piperazineacetamide hydrochloride; N-Acetyl-N'-(2-hydroxyethyl)piperazine hydrochloride; 2-[4-Acetylpiperazin-1-yl]ethanol hydrochloride; 1-Acetyl-4-(β-hydroxyethyl)piperazine HCl; AEHP HCl; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-(2-Hydroxy-Ethyl)-Piperazine Hcl is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.