Description

3,8-Dimethyl-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1174645-65-8. This heterocyclic compound is valued for its unique fused triazolo-pyrazine structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought by research and development organizations and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancer.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection and pesticide formulations.
• Organic Synthesis: Employed in academic and industrial laboratories for the construction of complex nitrogen-containing heterocycles.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and diagnostic applications due to its reactive sites.

Basic Information

Product Name	3,8-Dimethyl-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazine
CAS No.	1174645-65-8
Molecular Formula	C7H10N4
Molecular Weight	150.18 g/mol
Synonyms	3,8-Dimethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 5H,6H,7H,8H-[1,2,4]Triazolo[4,3-a]pyrazine, 3,8-dimethyl-; 3,8-Dimethyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine; 1174645-65-8; Triazolopyrazine derivative; Dimethyltetrahydrotriazolopyrazine
EINECS	Contact for details

Quality Control

Our 3,8-Dimethyl-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.