Description

tert-Butyl 5-formylpyrazine-2-carboxylate is a high-purity, versatile pyrazine derivative serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a formyl and a protected carboxylate group, makes it an indispensable intermediate for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for the preparation of functional organic materials, such as organic semiconductors and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis services catering to specialized R&D projects.

Basic Information

Product Name	tert-Butyl 5-Formylpyrazine-2-Carboxylate
CAS No.	1174321-08-4
Molecular Formula	C10H12N2O3
Molecular Weight	208.22 g/mol
Synonyms	5-Formylpyrazine-2-carboxylic acid tert-butyl ester; 2-Pyrazinecarboxylic acid, 5-formyl-, 1,1-dimethylethyl ester; tert-Butyl 5-formyl-2-pyrazinecarboxylate; 1,1-Dimethylethyl 5-formyl-2-pyrazinecarboxylate; 5-Formyl-2-pyrazinecarboxylic acid tert-butyl ester; TBFC; Pyrazine building block 1174321-08-4
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 5-formylpyrazine-2-carboxylate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing all critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.