Description

2-Formyl-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester (Wx140297) is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyrazine core and formyl protecting group. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, particularly for projects involving kinase inhibitors or other nitrogen-containing heterocyclic drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• API Development: Serves as a crucial building block in the production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Kinase Inhibitor Synthesis: Particularly valuable for constructing the core scaffold of potential kinase inhibitors due to its imidazopyrazine structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	2-Formyl-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester (Wx140297)
CAS No.	1174068-98-4
Molecular Formula	C13H17N3O3
Molecular Weight	263.29 g/mol
Synonyms	tert-Butyl 2-formyl-5,6-dihydro-8H-imidazo[1,2-a]pyrazine-7-carboxylate; 8H-Imidazo[1,2-a]pyrazine-7-carboxylic acid, 5,6-dihydro-2-formyl-, 1,1-dimethylethyl ester; WX-140297; Wx140297; BOC-protected formyl imidazopyrazine; 2-Formylimidazopyrazine tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Formyl-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.