Description

tert-Butyl 6-Formyl-3,4-Dihydropyrrolo[1,2-A]Pyrazine-2(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile building block for synthesizing complex molecules, enabling the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing innovative small-molecule drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for clinical research.
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing novel heterocyclic compounds during lead optimization and structure-activity relationship (SAR) studies.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the formyl-pyrrolopyrazine moiety into more complex molecular architectures.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and biological pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Item	Details
Product Name	tert-Butyl 6-Formyl-3,4-Dihydropyrrolo[1,2-A]Pyrazine-2(1H)-Carboxylate
CAS No.	1174068-79-1
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	tert-Butyl 6-formyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-2-carboxylate; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxaldehyde; 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-6-carboxaldehyde, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-Boc-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxaldehyde; 6-Formyl-2-Boc-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine; Boc-protected pyrrolopyrazine aldehyde; tert-Butyl 6-formyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Formyl-3,4-Dihydropyrrolo[1,2-A]Pyrazine-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.