Description

1-[4-(Ethylsulfonyl)-2-Nitrophenyl]Homopiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonyl and nitro-substituted aromatic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile building block for constructing heterocyclic compounds and functionalized piperazine derivatives.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Custom Synthesis: Supplied for contract research organizations (CROs) and CDMOs requiring specific, high-purity intermediates for client projects.

Basic Information

Product Name	1-[4-(Ethylsulfonyl)-2-Nitrophenyl]Homopiperazine Hydrochloride
CAS No.	1172507-82-2
Molecular Formula	C13H20ClN3O4S
Molecular Weight	349.83 g/mol
Synonyms	1-(4-Ethylsulfonyl-2-nitrophenyl)homopiperazine hydrochloride; 1-(4-(Ethylsulfonyl)-2-nitrophenyl)hexahydro-1H-1,4-diazepine hydrochloride; Homopiperazine, 1-[4-(ethylsulfonyl)-2-nitrophenyl]-, hydrochloride; 1172507-82-2; 1-(4-(Ethylsulfonyl)-2-nitrophenyl)-1,4-diazepane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[4-(Ethylsulfonyl)-2-Nitrophenyl]Homopiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.