Description

1-(Pyrrolidine-1-Carbonyl)Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its core value lies in its role as a versatile scaffold for constructing complex molecules, particularly in medicinal chemistry and drug discovery programs. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing focused libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in multi-step synthetic routes for the production of complex APIs.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and pesticides.
• Fine Chemical Synthesis: A valuable reagent for constructing complex heterocyclic compounds and specialty chemicals.
• Bioconjugation & Probe Development: Can be utilized in the development of biochemical probes and labeled compounds for diagnostic applications.

Basic Information

Product Name	1-(Pyrrolidine-1-Carbonyl)Piperazine Hydrochloride
CAS No.	1172232-02-8
Molecular Formula	C9H18ClN3O
Molecular Weight	219.71 g/mol
Synonyms	1-(1-Pyrrolidinecarbonyl)piperazine hydrochloride; Piperazine, 1-(1-pyrrolidinylcarbonyl)-, hydrochloride; 1-Piperazinecarboxamide, N-(pyrrolidinyl)-, hydrochloride; 1-(Pyrrolidine-1-carbonyl)piperazine HCl; 1-Pyrrolidinecarboxamide, N-(1-piperazinyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyrrolidine-1-Carbonyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.