Description

3-Amino-1-(Piperazin-1-Yl)Propan-1-One Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, biotechnology research firms, and fine chemical synthesis laboratories focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for new drug discovery.
• Bioconjugation & Probe Synthesis: Serves as a linker or precursor for creating biochemical probes and diagnostic agents.
• Chemical Biology: Utilized in the development of enzyme inhibitors and receptor modulators for biological pathway studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.

Basic Information

Product Name	3-Amino-1-(Piperazin-1-Yl)Propan-1-One Dihydrochloride
CAS No.	1171462-77-3
Molecular Formula	C7H16N3O • 2HCl
Molecular Weight	255.14 g/mol
Synonyms	1-(Piperazin-1-yl)-3-aminopropan-1-one dihydrochloride; 3-Amino-1-piperazin-1-ylpropan-1-one dihydrochloride; 3-Amino-1-(piperazin-1-yl)-1-propanone dihydrochloride; 1-Propanone, 3-amino-1-(1-piperazinyl)-, dihydrochloride; 3-Amino-1-(piperazin-1-yl)propan-1-one 2HCl; 3-Aminopropiopiperazine Dihydrochloride; 3-APP Dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-1-(Piperazin-1-Yl)Propan-1-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.