Description

2-(4-Trifluoromethylphenyl)-Piperazine Hydrochloride is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its piperazine scaffold and trifluoromethylphenyl group, which are critical for imparting desirable pharmacological and physicochemical properties to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the research and synthesis of potential central nervous system (CNS) agents, including antidepressants and antipsychotics.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex piperazine-derived compounds in medicinal chemistry.
• Material Science: Potential intermediate in the development of specialty polymers and advanced organic materials.
• Academic & R&D: Critical reagent for university and corporate research laboratories exploring new chemical entities and structure-activity relationships.

Basic Information

Item	Detail
Product Name	2-(4-Trifluoromethylphenyl)-Piperazine Hydrochloride
CAS No.	1171352-39-8
Molecular Formula	C11H14ClF3N2
Molecular Weight	266.69 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)piperazine hydrochloride; 4-(4-Trifluoromethylphenyl)piperazine hydrochloride; 1-[4-(Trifluoromethyl)phenyl]piperazine hydrochloride; 2-(4-Trifluoromethylphenyl)piperazine HCl; 4-(Trifluoromethyl)phenylpiperazine hydrochloride; 1-(4-Trifluoromethylphenyl)piperazine HCl; TFMPP hydrochloride (context-specific); α-(4-Trifluoromethylphenyl)-piperazine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Trifluoromethylphenyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.