Description

1-[2-(Methylsulfonyl)Phenyl]-3-Methylpiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and methylsulfonylphenyl moiety. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	1-[2-(Methylsulfonyl)Phenyl]-3-Methylpiperazine Hydrochloride
CAS No.	1171143-63-7
Molecular Formula	C12H18N2O2S • HCl
Molecular Weight	290.81 g/mol
Synonyms	3-Methyl-1-[2-(methylsulfonyl)phenyl]piperazine hydrochloride; 1-(2-Methanesulfonylphenyl)-3-methylpiperazine HCl; 3-Methyl-1-(2-methylsulfonylphenyl)piperazine hydrochloride; 1171143-63-7; 1-(2-Methylsulfonylphenyl)-3-methylpiperazine hydrochloride; 3-Methyl-1-(2-(methylsulfonyl)phenyl)piperazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-(Methylsulfonyl)Phenyl]-3-Methylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the stringent requirements for pharmaceutical R&D and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.