Description

1-(Pyrrolidin-1-Ylsulfonyl)Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block used in modern organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities and optimize lead compounds.
• Process Chemistry & Scale-up: Serves as a critical starting material or intermediate in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides, leveraging its sulfonyl-piperazine scaffold.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	1-(Pyrrolidin-1-Ylsulfonyl)Piperazine Hydrochloride
CAS No.	1171085-92-9
Molecular Formula	C9H19ClN3O2S
Molecular Weight	268.78 g/mol
Synonyms	1-(Pyrrolidine-1-sulfonyl)piperazine hydrochloride; 1-(1-Pyrrolidinylsulfonyl)piperazine hydrochloride; Piperazine, 1-(1-pyrrolidinylsulfonyl)-, hydrochloride; N-(Piperazin-1-ylsulfonyl)pyrrolidine hydrochloride; 1-Pyrrolidin-1-ylsulfonyl-piperazine HCl
EINECS	Contact for details

Quality Control

Our 1-(Pyrrolidin-1-Ylsulfonyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.