Description

1-[4-(Ethylsulfonyl)-2-Nitrophenyl]-4-Methylpiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine and nitrophenyl sulfone structure. This compound is of significant value in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for use in drug discovery programs and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for constructing complex heterocyclic compounds and studying structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides or pesticides, leveraging its sulfonyl and nitro functional groups.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical chemistry.
• Material Science: Potential use in the synthesis of specialty polymers or functional materials requiring specific piperazine-based monomers.

Basic Information

Product Name	1-[4-(Ethylsulfonyl)-2-Nitrophenyl]-4-Methylpiperazine Hydrochloride
CAS No.	1170982-65-6
Molecular Formula	C13H20ClN3O4S
Molecular Weight	349.83 g/mol
Synonyms	4-Methyl-1-[4-(ethylsulfonyl)-2-nitrophenyl]piperazine hydrochloride; 1-(4-Ethylsulfonyl-2-nitrophenyl)-4-methylpiperazine HCl; N-Ethylsulfonyl-2-nitro-N'-(4-methylpiperazin-1-yl)aniline hydrochloride; 1170982-65-6; 1-[4-(Ethylsulfonyl)-2-nitrophenyl]-4-methyl-piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-[4-(Ethylsulfonyl)-2-Nitrophenyl]-4-Methylpiperazine Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.