Description

[7-(2-Fluorophenyl)-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl]Acetic is a high-purity pharmaceutical intermediate and advanced building block with a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting neurological and oncological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those with pyrrolopyrazine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation molecules.
• Kinase Inhibitor Synthesis: Employed in the research and development of selective kinase inhibitors due to its privileged heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	[7-(2-Fluorophenyl)-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl]Acetic
CAS No.	1170575-17-3
Molecular Formula	C16H13FN2O3
Molecular Weight	300.29 g/mol
Synonyms	4-(Carboxymethyl)-7-(2-fluorophenyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 2-{7-(2-Fluorophenyl)-1-oxo-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-4-yl}acetic acid; 7-(2-Fluorophenyl)-4-(carboxymethyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 1170575-17-3; Pyrrolo[1,2-a]pyrazine-4-acetic acid derivative; Fluorophenyl pyrrolopyrazine acetic acid
EINECS	Contact for details

Quality Control

Our [7-(2-Fluorophenyl)-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl]Acetic is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full batch traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.