Description

1-[(2,3,5,6-Tetramethylphenyl)Sulfonyl]Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative designed for advanced chemical synthesis. This compound serves as a critical sulfonamide-protected piperazine building block, enabling the development of novel molecules with enhanced pharmacological properties. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the sulfonyl piperazine moiety can contribute to biological activity.
• Chemical Biology Probe Synthesis: Employed as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized building block for custom chemical synthesis services catering to the fine chemical and life science industries.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in organic chemistry and new reaction methodology development.

Basic Information

Product Name	1-[(2,3,5,6-Tetramethylphenyl)Sulfonyl]Piperazine Hydrochloride
CAS No.	1170478-53-1
Molecular Formula	C15H23ClN2O2S
Molecular Weight	330.87 g/mol
Synonyms	1-(2,3,5,6-Tetramethylbenzenesulfonyl)piperazine hydrochloride; 1-(2,3,5,6-Tetramethylphenylsulfonyl)piperazine HCl; Piperazine, 1-[(2,3,5,6-tetramethylphenyl)sulfonyl]-, hydrochloride; 1-(Duren-2-sulfonyl)piperazine hydrochloride; 1-(2,3,5,6-Tetramethylbenzene-1-sulfonyl)piperazine hydrochloride; Tetramethylphenylsulfonyl piperazine HCl; TMPS-Piperazine HCl
EINECS	Contact for details

Quality Control

Our 1-[(2,3,5,6-Tetramethylphenyl)Sulfonyl]Piperazine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.