Description

1-{[3-(4-Chlorophenyl)-1,2,4-Oxadiazol-5-Yl]Methyl}Piperazine Hydrochloride is a high-purity, non-nucleoside pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Biochemical Research: Used as a reference standard or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Development: Serves as a core scaffold in the development of new active pharmaceutical ingredients, especially those with oxadiazole and piperazine pharmacophores.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological testing.

Basic Information

Product Name	1-{[3-(4-Chlorophenyl)-1,2,4-Oxadiazol-5-Yl]Methyl}Piperazine Hydrochloride
CAS No.	1170477-01-6
Molecular Formula	C14H17ClN4O • HCl
Molecular Weight	329.23 g/mol (Free base: 292.77)
Synonyms	5-[(Piperazin-1-yl)methyl]-3-(4-chlorophenyl)-1,2,4-oxadiazole hydrochloride; 1-((3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl)methyl)piperazine hydrochloride; 3-(4-Chlorophenyl)-5-(piperazin-1-ylmethyl)-1,2,4-oxadiazole hydrochloride; 1,2,4-Oxadiazole, 3-(4-chlorophenyl)-5-[(1-piperazinyl)methyl]-, hydrochloride; 1170477-01-6; 1-{[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine HCl
EINECS	Contact for details

Quality Control

Our 1-{[3-(4-Chlorophenyl)-1,2,4-Oxadiazol-5-Yl]Methyl}Piperazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.