Description

Methyl 4-(2-Piperazinoethoxy)Benzenecarboxylate Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate and building block of significant commercial interest. Its core value lies in its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric research. This compound is essential for B2B clients in the pharmaceutical, biotechnology, and advanced fine chemical sectors who require reliable, high-quality raw materials for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• API Synthesis: Serves as a key chiral precursor in the production of specific, potent active pharmaceutical ingredients under current clinical investigation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Biochemical Research: Employed as a tool compound in biochemical assays to study receptor-ligand interactions and signal transduction pathways.
• Fine Chemical Production: Utilized in the synthesis of other complex, high-value specialty chemicals requiring a piperazine-ethoxy benzoate motif.

Basic Information

Product Name	Methyl 4-(2-Piperazinoethoxy)Benzenecarboxylate Hydrochloride
CAS No.	1170473-34-3
Molecular Formula	C14H21N2O3 • HCl
Molecular Weight	308.79 g/mol (Free base: 265.33 g/mol)
Synonyms	Methyl 4-[2-(piperazin-1-yl)ethoxy]benzoate hydrochloride; 4-[2-(1-Piperazinyl)ethoxy]benzoic Acid Methyl Ester Hydrochloride; Benzoic acid, 4-[2-(1-piperazinyl)ethoxy]-, methyl ester, hydrochloride; Methyl p-(2-piperazinoethoxy)benzoate HCl; (R/S)-Methyl 4-(2-piperazin-1-yl-ethoxy)benzoate hydrochloride; UNII-9F6J8S8R4S (component); Methyl 4-(2-(piperazin-1-yl)ethoxy)benzoate monohydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 4-(2-Piperazinoethoxy)Benzenecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.