Description

Methyl 6-Chloro-3-Methylpyrazine-2-Carboxylate is a high-purity pyrazine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its functionalized structure, which serves as a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the pyrazine core for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for creating new heterocyclic compounds and functional materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and in the development of organocatalysts.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty materials requiring a functionalized pyrazine moiety.

Basic Information

Product Name	Methyl 6-Chloro-3-Methylpyrazine-2-Carboxylate
CAS No.	1166831-45-3
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	Methyl 6-chloro-3-methylpyrazine-2-carboxylate; 6-Chloro-3-methylpyrazine-2-carboxylic acid methyl ester; Methyl 6-chloro-3-methyl-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 6-chloro-3-methyl-, methyl ester; 6-Chloro-3-methyl-2-pyrazinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloro-3-Methylpyrazine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.