Description

3-Bromo-4-(1-Boc-Piperizin-4-Yl)Nitrobenzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine and nitrobenzene scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Protease Inhibitor Development: Its structural features make it valuable for constructing molecules that target specific protease enzymes.
• Kinase Inhibitor Synthesis: Employed in the creation of potential kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to the pharmaceutical and biotech industries.

Basic Information

Product Name	3-Bromo-4-(1-Boc-Piperizin-4-Yl)Nitrobenzene
CAS No.	1163126-69-9
Molecular Formula	C16H22BrN3O4
Molecular Weight	400.27 g/mol
Synonyms	1-Boc-4-(2-Bromo-5-nitrophenyl)piperazine; tert-Butyl 4-(2-bromo-5-nitrophenyl)piperazine-1-carboxylate; 4-(2-Bromo-5-nitrophenyl)-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-bromo-5-nitrophenyl)piperazine; 3-Bromo-4-(1-Boc-piperazin-4-yl)nitrobenzene; 3-Bromo-4-(N-Boc-piperazin-4-yl)nitrobenzene; BOC-Piperazine Nitrobenzene Bromo Derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(1-Boc-Piperizin-4-Yl)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.