Description

5-Chloro-n-(2-Pyrrolidin-1-Ylethyl)Pyrazine-2-Carboxamide is a specialized heterocyclic compound featuring a pyrazine core functionalized with a chloro group and a carboxamide linker to a pyrrolidine-containing side chain. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Building Block: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Research: Employed in the development of novel herbicides or fungicides due to its heterocyclic scaffold.
• Chemical Biology Probe: Acts as a tool compound for investigating enzyme inhibition or receptor modulation in biochemical assays.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-functionalized heterocycles.

Basic Information

Product Name	5-Chloro-n-(2-Pyrrolidin-1-Ylethyl)Pyrazine-2-Carboxamide
CAS No.	1160264-34-5
Molecular Formula	C11H15ClN4O
Molecular Weight	254.72 g/mol
Synonyms	5-Chloro-N-[2-(1-pyrrolidinyl)ethyl]-2-pyrazinecarboxamide; 5-Chloro-N-(2-(pyrrolidin-1-yl)ethyl)pyrazine-2-carboxamide; 2-Pyrazinecarboxamide, 5-chloro-N-[2-(1-pyrrolidinyl)ethyl]-; 1160264-34-5; UNII-8J7F6R8Z4N; 8J7F6R8Z4N; SCHEMBL2180643; AKOS040759039
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-n-(2-Pyrrolidin-1-Ylethyl)Pyrazine-2-Carboxamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.