Description

6-Chloro-2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its bifunctional nature, featuring both a reactive acid chloride group and a halogenated quinoline core, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other quinoline-based therapeutic pathways.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides that leverage the quinoline scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and fluorescent tags for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	6-Chloro-2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-39-7
Molecular Formula	C20H15Cl2NO2
Molecular Weight	372.25 g/mol
Synonyms	6-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Isopropoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-[4-(1-methylethoxy)phenyl]-; 6-Chloro-2-(4-propan-2-yloxyphenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment is to supply material that meets the stringent requirements of research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.