Description

2-(4-tert-Butylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex molecular architectures, particularly in the development of specialized fine chemicals and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with quinoline-based scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its structural complexity for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the synthesis of organic electronic materials, dyes, and pigments due to the quinoline core's photophysical properties.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring a specific, functionalized quinoline derivative.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical reactions in laboratory settings.

Basic Information

Product Name	2-(4-tert-Butylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160262-73-6
Molecular Formula	C22H22ClNO
Molecular Weight	351.87 g/mol
Synonyms	6,8-Dimethyl-2-[4-(1,1-dimethylethyl)phenyl]-4-quinolinecarbonyl chloride; 2-(4-tert-Butylphenyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6,8-dimethyl-2-[4-(1,1-dimethylethyl)phenyl]-; 2-(p-tert-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride; TBPDMQ-CC; 1160262-73-6 (CAS); 2-(4-(tert-Butyl)phenyl)-6,8-dimethylquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-tert-Butylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.