Description

7,8-Dimethyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinoline scaffold for bioactive molecule design.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in organic laboratories for amide bond formation and as a versatile reagent for introducing the quinoline-4-carbonyl moiety into target molecules.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing complex heterocyclic dyes and fluorescent markers.

Basic Information

Product Name	7,8-Dimethyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160261-34-6
Molecular Formula	C20H16ClNO
Molecular Weight	321.80 g/mol
Synonyms	2-(p-Tolyl)-7,8-dimethylquinoline-4-carbonyl chloride; 4-Carbonyl chloride-7,8-dimethyl-2-(4-methylphenyl)quinoline; 7,8-Dimethyl-2-(4-methylphenyl)-4-quinolinecarbonyl chloride; 2-(4-Methylphenyl)-7,8-dimethylquinoline-4-carbonyl chloride; 7,8-Dimethyl-2-(p-tolyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 7,8-Dimethyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.