Description

2-(2-Chlorophenyl)-6-Ethylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides that leverage the quinoline structure for enhanced biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Dye & Pigment Synthesis: Acts as a core structure for developing specialized quinoline-based dyes and colorants with specific light-fastness properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems used in cross-coupling and other synthetic transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-(2-Chlorophenyl)-6-Ethylquinoline-4-Carbonyl Chloride
CAS No.	1160260-93-4
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	6-Ethyl-2-(2-chlorophenyl)quinoline-4-carbonyl chloride; 2-(2-Chlorophenyl)-6-ethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(2-chlorophenyl)-6-ethyl-; 1160260-93-4; 2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(2-Chlorophenyl)-6-Ethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.