Description

7-Chloro-2-(2,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of critical importance for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel quinoline-based drug candidates, particularly in oncology and antiviral research.
• Organic Synthesis Building Block: Used in amide coupling and esterification reactions to introduce the quinoline scaffold into more complex molecular architectures.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline core.
• Material Science: Potential use in the synthesis of organic ligands for catalytic systems or functional materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Item	Detail
Product Name	7-Chloro-2-(2,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160256-48-3
Molecular Formula	C20H15Cl2NO
Molecular Weight	356.25 g/mol
Synonyms	4-Chlorocarbonyl-7-chloro-2-(2,4-dimethylphenyl)-8-methylquinoline; 7-Chloro-2-(2,4-dimethylphenyl)-8-methyl-4-quinolinecarbonyl chloride; 7-Chloro-8-methyl-2-(2,4-dimethylphenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 7-chloro-2-(2,4-dimethylphenyl)-8-methyl-; CAS 1160256-48-3
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(2,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.