Description

8-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and complex quinoline-based aromatic structure. This compound matters for its critical role as a versatile building block in the synthesis of advanced pharmaceutical agents and sophisticated organic materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Catalyst & Ligand Development: The quinoline structure can be modified to create novel ligands for metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential for organic chemistry research in universities and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	8-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160256-38-1
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	8-Chloro-2-(3,4-dimethylphenyl)quinoline-4-carbonyl chloride; 2-(3,4-Dimethylphenyl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-(3,4-dimethylphenyl)-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 8-chloro-2-(3,4-dimethylphenyl)-; 1160256-38-1
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP (current Good Manufacturing Practice) environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.