Description

2-(2-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. This compound is critical for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity building block for constructing novel quinoline-based structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with quinoline scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the biological activity of functionalized quinolines.
• Material Science: Serves as a precursor for creating specialized ligands, catalysts, and functional organic materials.
• Chemical Synthesis: A versatile reagent for introducing the 2-(2-isopropoxyphenyl)-8-methylquinoline moiety into more complex molecular architectures via its reactive carbonyl chloride group.
• Academic & Industrial R&D: Employed in research laboratories for method development and the exploration of new chemical entities.

Basic Information

Product Name	2-(2-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-73-8
Molecular Formula	C20H18ClNO2
Molecular Weight	339.82 g/mol
Synonyms	8-Methyl-2-[2-(propan-2-yloxy)phenyl]quinoline-4-carbonyl chloride; 2-(2-Isopropoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[2-(1-methylethoxy)phenyl]-8-methyl-; 2-(2-Isopropoxyphenyl)-8-methylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(2-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.