Description

8-Methyl-2-(4-Propylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, enabling the development of novel compounds with targeted properties. This product is critically needed by research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of potential active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Chemical Synthesis: An acyl chloride reagent for introducing the 8-methyl-2-(4-propylphenyl)quinoline-4-carbonyl moiety into target molecules via amidation or esterification reactions.
• Ligand & Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable tool for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	8-Methyl-2-(4-Propylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160254-23-8
Molecular Formula	C21H20ClNO
Molecular Weight	337.84 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 8-methyl-2-[4-(1-methylethyl)phenyl]-; 2-(4-Isopropylphenyl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-(4-propan-2-ylphenyl)quinoline-4-carbonyl chloride; 8-Methyl-2-(p-isopropylphenyl)-4-quinolinecarbonyl chloride; 8-Methyl-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride; MPQC-Cl; (8-Methyl-2-(4-propylphenyl)quinolin-4-yl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.