Description

2-(3-Isobutoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex molecules, offering a versatile building block for constructing quinoline-based pharmacophores. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and anti-infective agents.
• Organic Synthesis Building Block: Used in amide coupling reactions to introduce the 2-(3-Isobutoxyphenyl)-6-methylquinoline moiety into larger molecular architectures.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and pesticides with quinoline scaffolds.
• Material Science: Investigated for the creation of specialized organic ligands and functional materials due to its distinct aromatic structure.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	2-(3-Isobutoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160253-97-3
Molecular Formula	C22H22ClNO2
Molecular Weight	367.87 g/mol
Synonyms	6-Methyl-2-[3-(2-methylpropoxy)phenyl]quinoline-4-carbonyl chloride; 2-(3-Isobutoxyphenyl)-6-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[3-(2-methylpropoxy)phenyl]-6-methyl-; 1160253-97-3; AI3-72999; ZINC19764295
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Isobutoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.