Description

2-(4-Chlorophenyl)-6-Methylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters as a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new compounds with specific biological or functional properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential anticancer, antiviral, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and functional polymers.
• Chemical Biology: Employed as a probe or tagging reagent in biochemical research due to its reactive acid chloride group.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized quinoline-derived colorants and optical brighteners.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule development projects.

Basic Information

Product Name	2-(4-Chlorophenyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160253-67-7
Molecular Formula	C18H11Cl2NO
Molecular Weight	328.19 g/mol
Synonyms	6-Methyl-2-(4-chlorophenyl)quinoline-4-carbonyl chloride; 2-(p-Chlorophenyl)-6-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(4-chlorophenyl)-6-methyl-; 2-(4-Chlorophenyl)-6-methylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-6-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.