Description

2-Bromo-5-Ethoxy-4-Methoxybenzoyl Chloride is a high-purity, multi-functional benzoyl chloride derivative designed for advanced organic synthesis. This compound serves as a critical acylating agent and versatile building block for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators, leveraging the bromo and alkoxy substituents for bioactivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Intermediate in the production of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Employed in research-scale and pilot-scale campaigns for custom molecule synthesis under cGMP or ISO standards.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development due to its reactive acid chloride group.

Basic Information

Product Name	2-Bromo-5-Ethoxy-4-Methoxybenzoyl Chloride
CAS No.	1160250-72-5
Molecular Formula	C10H10BrClO3
Molecular Weight	293.54 g/mol
Synonyms	4-Methoxy-5-ethoxy-2-bromobenzoyl chloride; 5-Ethoxy-4-methoxy-2-bromobenzoic acid chloride; 2-Bromo-4-methoxy-5-ethoxybenzoyl chloride; (2-Bromo-5-ethoxy-4-methoxyphenyl)carbonyl chloride; Benzoyl chloride, 2-bromo-5-ethoxy-4-methoxy-; 1160250-72-5; 2-Bromo-5-ethoxy-4-methoxy-benzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Ethoxy-4-Methoxybenzoyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistency, purity, and traceability for your critical R&D and production processes. Certificates of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.