Description

4-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride is a high-purity, reactive organic intermediate characterized by its benzoyl chloride core functionalized with a 2-fluorobenzyloxy substituent. This compound is of significant value for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced organic electronic materials due to its aromatic structure and functional groups suitable for further coupling reactions.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group is utilized for amide bond formation, making it valuable for creating peptide analogs and linker molecules in bioconjugation chemistry.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with specific thermal or optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis, including Suzuki-Miyaura and other cross-coupling reactions.

Basic Information

Product Name	4-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160249-64-8
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	4-[(2-Fluorophenyl)methoxy]benzoyl chloride; 2-Fluorobenzyl 4-(chlorocarbonyl)phenyl ether; p-[(2-Fluorobenzyl)oxy]benzoyl chloride; Benzoyl chloride, 4-[(2-fluorobenzyl)oxy]-; (4-((2-Fluorobenzyl)oxy)phenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 4-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.