Description

8-Ethoxy-2-Oxo-2H-Chromene-3-Carbonyl Chloride is a high-purity, reactive organic intermediate belonging to the coumarin derivative family. This compound is a critical building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with coumarin-based scaffolds targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides where the coumarin structure imparts specific biological activity.
• Fluorescent Probe & Dye Manufacturing: Serves as a foundational material for creating advanced fluorescent dyes, molecular probes, and sensors used in bio-imaging and diagnostics.
• Organic Synthesis & Material Science: An essential acylating agent and building block for constructing complex heterocyclic compounds and functional polymers in academic and industrial research.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals for diverse industrial applications.

Basic Information

Product Name	8-Ethoxy-2-Oxo-2H-Chromene-3-Carbonyl Chloride
CAS No.	1160249-14-8
Molecular Formula	C₁₃H₉ClO₄
Molecular Weight	264.66 g/mol
Synonyms	8-Ethoxycoumarin-3-carbonyl chloride; 8-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride; 3-Chlorocarbonyl-8-ethoxycoumarin; 8-Ethoxy-2-oxochromene-3-carbonyl chloride; 8-Ethoxy-2H-chromene-2-one-3-carbonyl chloride; 8-Ethoxy-2-oxo-2H-chromene-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 8-Ethoxy-2-Oxo-2H-Chromene-3-Carbonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity (by IR and NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.