Description

5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its acyl chloride functionality, which enables efficient coupling reactions to construct complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those containing thiophene and biphenyl-like motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carbonyl Chloride
CAS No.	1160249-01-3
Molecular Formula	C13H11ClOS
Molecular Weight	250.74 g/mol
Synonyms	4-(4-Methylphenyl)-5-methylthiophene-3-carbonyl chloride; 5-Methyl-4-(p-tolyl)thiophene-3-carbonyl chloride; 3-Thiophenecarbonyl chloride, 5-methyl-4-(4-methylphenyl)-; 4-(p-Tolyl)-5-methyl-3-thiophenecarbonyl chloride; 1160249-01-3; 5-Methyl-4-(4-methylphenyl)thiophene-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.