Description

4-((2-Methoxyphenylsulfonyl)Methyl)Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylmethylpiperidine scaffold. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. Pharmaceutical R&D teams and fine chemical manufacturers need it for developing new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperidine and sulfonyl functional groups.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of protease inhibitors, leveraging the sulfonamide moiety.
• Ligand Synthesis for Drug Discovery: Employed in creating specialized ligands for high-throughput screening and target identification.
• Fine Chemical Synthesis: Intermediate for producing more complex, high-value specialty chemicals used in agrochemical and material science applications.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) engaged in cutting-edge organic synthesis projects.

Basic Information

Product Name	4-((2-Methoxyphenylsulfonyl)Methyl)Piperidine
CAS No.	1160245-64-6
Molecular Formula	C14H21NO3S
Molecular Weight	283.39 g/mol
Synonyms	4-[(2-Methoxyphenyl)sulfonylmethyl]piperidine; 1-[(2-Methoxyphenyl)sulfonylmethyl]-4-piperidine; 4-((2-Methoxyphenylsulfonyl)methyl)piperidine; Piperidine, 4-[(2-methoxyphenyl)sulfonylmethyl]-; 4-(2-Methoxy-benzenesulfonylmethyl)-piperidine; 4-(2-Methoxy-phenylsulfonylmethyl)-piperidine; 1160245-64-6
EINECS	Contact for details

Quality Control

Our 4-((2-Methoxyphenylsulfonyl)Methyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.