Description

4-Methyl-n-[(1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methyl]-n-Phenylbenzamide Hydrochloride is a high-purity, non-racemic organic compound of significant interest in advanced pharmaceutical research and development. This molecule, supplied as a hydrochloride salt, offers enhanced stability and solubility for critical process development and analytical work. It is primarily utilized by research scientists and process chemists in the pharmaceutical and biotechnology sectors. This compound serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in drug discovery and development pipelines.
• Biochemical Research: Employed in vitro and in vivo studies to investigate biological pathways, receptor binding, and pharmacological activity.
• Process Chemistry: Serves as a starting material or advanced intermediate for scale-up and optimization of synthetic routes under GMP or non-GMP conditions.
• Library Synthesis: Used in medicinal chemistry for the creation of focused compound libraries to explore structure-activity relationships (SAR).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	4-Methyl-n-[(1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methyl]-n-Phenylbenzamide Hydrochloride
CAS No.	1160245-44-2
Molecular Formula	C24H26N4O · HCl
Molecular Weight	422.95 g/mol (Free base: 386.50 g/mol)
Synonyms	4-Methyl-N-[(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methyl]-N-phenylbenzamide hydrochloride; 4-Methyl-N-[(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methyl]-N-phenyl-benzamide HCl; Benzamide, 4-methyl-N-[(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methyl]-N-phenyl-, hydrochloride (1:1); UNII-8G3F6WY0QN; 8G3F6WY0QN; SCHEMBL23306277; AKOS040757623; BDBM50389363.
EINECS	Contact for details

Quality Control

Our 4-Methyl-n-[(1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methyl]-n-Phenylbenzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.