Description

1-Boc-4-Amino-4-Piperidineacetic Acid is a high-purity, protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical versatile building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Synthesis: Used to incorporate constrained, unnatural amino acid motifs into peptide chains to enhance stability and biological activity.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for drug discovery campaigns.
• Linker Molecule in Bioconjugation: Serves as a functional spacer or linker in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Research: Acts as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer for specialty polymers and advanced materials with specific functional properties.

Basic Information

Product Name	1-Boc-4-Amino-4-Piperidineacetic Acid
CAS No.	1159983-30-8
Molecular Formula	C₁₂H₂₂N₂O₄
Molecular Weight	258.31 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-4-piperidineacetic acid; 4-(Boc-amino)-4-piperidineacetic acid; 4-Amino-1-Boc-piperidine-4-acetic acid; 1-Boc-4-aminoisonipecotic acid; 4-(tert-Butoxycarbonylamino)piperidine-4-acetic acid; 4-(Boc-amino)isonipecotic acid; tert-Butyl 4-amino-4-(carboxymethyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Amino-4-Piperidineacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP and ISO 9001 standards where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.