Description

tert-Butyl 9-Benzyl-2,9-Diazaspiro[5.5]Undecane-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiroalkane class of compounds. This molecule serves as a critical building block in modern medicinal chemistry, enabling the synthesis of complex, three-dimensional structures essential for drug discovery. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutics, particularly in the areas of central nervous system (CNS) disorders and other disease targets requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery & Development: Integral to the development of novel drug candidates, especially those requiring spirocyclic and constrained amine motifs for enhanced receptor binding and metabolic stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity, complex intermediates.

Basic Information

Product Name	tert-Butyl 9-Benzyl-2,9-Diazaspiro[5.5]Undecane-2-Carboxylate
CAS No.	1159982-59-8
Molecular Formula	C21H32N2O2
Molecular Weight	344.50 g/mol
Synonyms	2,9-Diazaspiro[5.5]undecane-2-carboxylic acid, 9-(phenylmethyl)-, 1,1-dimethylethyl ester; 9-Benzyl-2,9-diazaspiro[5.5]undecane-2-carboxylic acid tert-butyl ester; tert-Butyl 9-benzyl-2,9-diazaspiro[5.5]undecane-2-carboxylate; 9-Benzyl-2-tert-butoxycarbonyl-2,9-diazaspiro[5.5]undecane; BOC-9-Benzyl-2,9-diazaspiro[5.5]undecane; 1159982-59-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 9-Benzyl-2,9-Diazaspiro[5.5]Undecane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply of this high-value intermediate for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.