Description

1-Acetyl-2-Methylazepane-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique azepane ring structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile chiral building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential protease inhibitors due to its constrained cyclic amine structure.
• Asymmetric Synthesis: Employed as a starting material or intermediate in asymmetric catalytic reactions to introduce stereochemical complexity.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.

Basic Information

Product Name	1-Acetyl-2-Methylazepane-2-Carboxylic Acid
CAS No.	1159824-79-9
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	2-Methyl-1-acetylazepane-2-carboxylic acid; 2-Methyl-2-carboxy-1-acetylazepane; 1-Acetyl-2-methyl-2-azepanecarboxylic acid; (2-Methylazepan-2-yl)(oxo)acetic acid acetate; Azepane-2-carboxylic acid, 1-acetyl-2-methyl-; 1159824-79-9; 2-Methyl-1-(acetyl)azepane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Acetyl-2-Methylazepane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.