Description

3-Methyl-Piperidine-4-Carboxylic Acid Ethyl Ester Hydrochloride is a high-purity piperidine derivative salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a functionalized, nitrogen-containing scaffold essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides requiring specific stereochemical configurations.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex heterocyclic compounds.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	3-Methyl-Piperidine-4-Carboxylic Acid Ethyl Ester Hydrochloride
CAS No.	1159822-87-3
Molecular Formula	C10H20ClNO2
Molecular Weight	221.72 g/mol
Synonyms	Ethyl 3-Methylpiperidine-4-carboxylate hydrochloride; 4-Carbethoxy-3-methylpiperidine hydrochloride; 3-Methylisonipecotic acid ethyl ester hydrochloride; 3-Methyl-4-piperidinecarboxylic acid ethyl ester hydrochloride; 1,2,3,6-Tetrahydro-3-methyl-4-pyridinecarboxylic acid ethyl ester hydrochloride (tautomeric form); 3-Methyl-4-(ethoxycarbonyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Methyl-Piperidine-4-Carboxylic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.