Description

2-Bromo-5-(tert-Butoxy)Pyrazine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and alkoxy-substituted structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands used in catalytic systems and material science.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry and scale-up process optimization.

Basic Information

Product Name	2-Bromo-5-(tert-Butoxy)Pyrazine
CAS No.	1159816-36-0
Molecular Formula	C8H11BrN2O
Molecular Weight	231.09 g/mol
Synonyms	2-Bromo-5-(tert-butoxy)pyrazine; 5-(tert-Butoxy)-2-bromopyrazine; 2-Bromo-5-tert-butoxypyrazine; Pyrazine, 2-bromo-5-(1,1-dimethylethoxy)-; tert-Butyl 6-bromopyrazin-3-yl ether
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(tert-Butoxy)Pyrazine is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is essential for reproducible research and process scale-up. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.