Description

5-(Tetrahydro-2H-Pyran-4-Yl)Pyrazin-2-Amine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate complex pyrazine and tetrahydropyran motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for bioactivity.
• Material Science Precursor: Serves as a building block for creating novel organic ligands, catalysts, or functional polymers with tailored properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	5-(Tetrahydro-2H-Pyran-4-Yl)Pyrazin-2-Amine
CAS No.	1159815-73-2
Molecular Formula	C9H13N3O
Molecular Weight	179.22 g/mol
Synonyms	5-(Tetrahydro-2H-pyran-4-yl)pyrazin-2-amine; 5-(Oxan-4-yl)pyrazin-2-amine; 2-Amino-5-(tetrahydro-2H-pyran-4-yl)pyrazine; 5-(Tetrahydro-2H-pyran-4-yl)-2-pyrazinamine; 1159815-73-2; 5-(THP-4-yl)pyrazin-2-amine; 5-(Tetrahydropyran-4-yl)pyrazin-2-amine
EINECS	Contact for details

Quality Control

Our 5-(Tetrahydro-2H-Pyran-4-Yl)Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.