Description

1-(Pyrazin-2-Yl)Cyclopropan-1-Amine is a high-purity, nitrogen-containing heterocyclic building block featuring a cyclopropylamine moiety. This compound is valued for its unique structural motif, which is critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry and as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce conformational constraint and improve metabolic stability.
• Agrochemical Synthesis: Serves as a key precursor in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with tailored properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	1-(Pyrazin-2-Yl)Cyclopropan-1-Amine
CAS No.	1159734-56-1
Molecular Formula	C7H9N3
Molecular Weight	135.17 g/mol
Synonyms	1-(Pyrazin-2-yl)cyclopropanamine; 1-Aminocyclopropanecarbonitrile; 1-Cyclopropyl-2-pyrazinamine; 2-(1-Aminocyclopropyl)pyrazine; 1-(2-Pyrazinyl)cyclopropanamine; 1-Pyrazin-2-ylcyclopropan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(Pyrazin-2-Yl)Cyclopropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures material integrity for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.