Description

1-(Pyrazin-2-Yl)Cyclopropanecarboxylic Acid is a high-value, multifunctional heterocyclic building block featuring a cyclopropane ring fused to a pyrazine-carboxylic acid moiety. This unique structure makes it a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and tools for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1-(Pyrazin-2-Yl)Cyclopropanecarboxylic Acid
CAS No.	1159734-52-7
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	2-Cyclopropylcarbonylpyrazine; Cyclopropanecarboxylic acid, 1-(2-pyrazinyl)-; 1-Pyrazin-2-ylcyclopropanecarboxylic acid; 1-(2-Pyrazinyl)cyclopropanecarboxylic Acid; 1-(Pyrazin-2-yl)cyclopropanecarboxylic acid; 1159734-52-7; 2-Cyclopropanecarbonylpyrazine
EINECS	Contact for details

Quality Control

Our 1-(Pyrazin-2-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider inert atmosphere packaging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.