Description

1-(Pyrazin-2-Yl)Cyclopropanecarbonitrile is a high-value, nitrogen-rich heterocyclic building block featuring a cyclopropane ring fused with a pyrazine-carbonitrile moiety. This compound is essential for medicinal chemistry research and development, serving as a key precursor for synthesizing novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in the areas of kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of potential kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	1-(Pyrazin-2-Yl)Cyclopropanecarbonitrile
CAS No.	1159734-50-5
Molecular Formula	C8H7N3
Molecular Weight	145.16 g/mol
Synonyms	1-(Pyrazin-2-yl)cyclopropanecarbonitrile; 2-(1-Cyanocyclopropyl)pyrazine; Cyclopropanecarbonitrile, 1-(2-pyrazinyl)-; 1-Pyrazin-2-ylcyclopropanecarbonitrile; 1159734-50-5; 1-(2-Pyrazinyl)cyclopropanecarbonitrile; Pyrazine, 2-(1-cyanocyclopropyl)-
EINECS	Contact for details

Quality Control

Our 1-(Pyrazin-2-Yl)Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.