Description

3-(4-Fluoro-Benzyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine chemical class. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by R&D chemists, process development scientists, and manufacturers in the global pharmaceutical and biotechnology sectors requiring reliable, high-quality intermediates for drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological disorders.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a key fragment in the construction of complex API molecules for preclinical and clinical trials.
• Biochemical Research: Employed as a tool compound or a ligand in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up production under current Good Manufacturing Practice (cGMP) guidelines.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and pharmacological studies.

Basic Information

Product Name	3-(4-Fluoro-Benzyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine
CAS No.	1159553-30-6
Molecular Formula	C₁₂H₁₃FN₄
Molecular Weight	232.26 g/mol
Synonyms	3-[(4-Fluorophenyl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 1,2,4-Triazolo[4,3-a]pyrazine, 3-[(4-fluorophenyl)methyl]-5,6,7,8-tetrahydro-; 3-(4-Fluorobenzyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine; 1159553-30-6; AKOS025146192; FT-0776058; EN300-251294; A937183
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to strict quality management protocols suitable for pharmaceutical R&D and can supply material produced under quality systems aligned with ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.