Description

3-Cyclobutyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine chemical class. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Drug Discovery Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its privileged heterocyclic structure.
• CNS Drug Development: Employed in the research of potential treatments for neurological and psychiatric disorders.
• Oncology Research: Utilized as a building block for developing small-molecule inhibitors and targeted cancer therapies.
• Chemical Biology Probe Synthesis: Acts as a core structure for creating tool compounds to study biological mechanisms and protein function.
• Agrochemical Research: Potential application in the development of new crop protection agents and pesticides.

Basic Information

Product Name	3-Cyclobutyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.	1159530-85-4
Molecular Formula	C11H16N4
Molecular Weight	204.27 g/mol
Synonyms	3-Cyclobutyl-4,5,6,7-tetrahydro-1H-[1,2,4]triazolo[4,3-a]pyrazine; 3-Cyclobutyl-4,5,6,7-tetrahydro-2H-[1,2,4]triazolo[4,3-a]pyrazine; 1159530-85-4; 3-Cyclobutyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine; 3-Cyclobutyl-4,5,6,7-tetrahydro-1H-[1,2,4]triazolo[4,3-a]pyrazine; Triazolopyrazine derivative CAS 1159530-85-4
EINECS	Contact for details

Quality Control

Our 3-Cyclobutyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.