Description

1-(4-Methyl-Benzyl)-Piperidin-4-Ylamine Hydrochloride CAS NO 1158779-16-8 is a high-purity, functionalized piperidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other therapeutic agents.
• Agrochemical Research: Used as a building block for developing new crop protection agents, herbicides, and pesticides.
• Chemical Synthesis: Serves as a versatile amine component in amide coupling reactions, reductive amination, and the preparation of complex heterocycles.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts.
• Life Sciences Research: Utilized in biochemical and pharmacological studies as a tool compound for probing biological pathways.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and functional materials.

Basic Information

Product Name	1-(4-Methyl-Benzyl)-Piperidin-4-Ylamine Hydrochloride
CAS No.	1158779-16-8
Molecular Formula	C14H23ClN2
Molecular Weight	254.80 g/mol
Synonyms	4-Amino-1-[(4-methylphenyl)methyl]piperidine hydrochloride; 1-[(4-Methylphenyl)methyl]-4-piperidinamine hydrochloride; 1-(4-Methylbenzyl)piperidin-4-amine HCl; 4-Amino-1-(4-methylbenzyl)piperidine HCl; 1-(p-Methylbenzyl)-4-aminopiperidine hydrochloride; 4-Piperidinamine, 1-[(4-methylphenyl)methyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(4-Methyl-Benzyl)-Piperidin-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.