Description

8-Methyl-2,8-Diazaspiro[4.5]Decane (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is a critical building block in modern medicinal chemistry, valued for its unique three-dimensional structure that can enhance the binding affinity and selectivity of drug candidates. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly within the central nervous system (CNS) and oncology drug pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Scaffold: Used as a privileged spirocyclic scaffold for constructing compound libraries in high-throughput screening and lead optimization.
• CNS Drug Development: Employed in the synthesis of potential therapeutics targeting neurological disorders, such as depression, anxiety, and schizophrenia.
• Oncological Research: Serves as a building block for novel small-molecule inhibitors and targeted cancer therapies.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.

Basic Information

Product Name	8-Methyl-2,8-Diazaspiro[4.5]Decane (Saltdata: Free)
CAS No.	1158750-98-1
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	8-Methyl-2,8-diazaspiro[4.5]decane; 2,8-Diazaspiro[4.5]decane, 8-methyl-; 8-Methyl-2,8-diazaspiro[4.5]decane free base; 8-Methyl-2,8-diazaspiro[4.5]decane (base); 1158750-98-1; Spiro[4.5]decane, 8-methyl-2,8-diaza-; 8-Methyl-2,8-diaza-spiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 8-Methyl-2,8-Diazaspiro[4.5]Decane (Saltdata: Free) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.