Description

1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Amine Hydrochloride is a high-purity sulfonamide derivative and a key pharmaceutical intermediate. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring a functionalized piperidine core with a sulfonyl-protected amine.
• Biochemical Research: May be utilized in the development of chemical probes or inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Amine Hydrochloride
CAS No.	1158356-14-9
Molecular Formula	C12H19ClN2O2S
Molecular Weight	290.81 g/mol
Synonyms	4-Amino-1-(p-tolylsulfonyl)piperidine Hydrochloride; 1-(4-Methylbenzenesulfonyl)piperidin-4-amine Hydrochloride; 4-Amino-1-tosylpiperidine Hydrochloride; 1-(p-Toluenesulfonyl)-4-piperidinamine Hydrochloride; 4-Amino-1-(4-methylphenylsulfonyl)piperidine HCl; N-(4-Methylphenylsulfonyl)-4-piperidinamine Hydrochloride; 1-Tosyl-4-piperidinamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.